PredatorCMS is the CMS which powers most of the bigger tube sites, it's a bit expensive but it's very functional.

As for servers, if you're going to host the videos yourself, you can't just get one server, you will need a few. You can use one for the webserver+DB, one as an encoding server and the others as fileservers. It all depends on how YOU want your setup to be. Another thing, a dedicated 1Gbps connection is minimum requirements, a preferred 2-10Gbps connection will be necessary if you expect your site to grow exponentially.

I mentioned a dedicated connection because depending on what type of files you convert to (flv/mp4), the filesizes will affect how much bandwidth you utilize. Multiple concurrent streams will utilize a lot of bandwidth and some providers frown at the idea of having a streaming site on their network, so clarify it with your host before you start

DMCA, it's up to you how you will deal with it.

Monetisation is easy as there are a multitude of companies that specialize in adult tube sites. Just google around.
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