FTP is the best and fastest method for most file hosts.
file & image uploader is ok for mu cause it give the download links after the upload is done. but it makes to many errors, the uploads breaks up and sometimes the files don't go into your account.
few times after the upload was done, when I checked in MU file manager I saw some files are missing but all download links given in file & image uploader worked fine. so with file & image uploader sometimes the files are uploaded on megaupload but not in your account.