Comodo has a lot of good features, but i wouldn't say its the best, not in the top 10 even.
There was a time when i was involved in lets say blackhat activities, and as a part of the process i would have to deal with AV engines and their detection techniques. The biggest problems i had was with Avira. All others were pretty easy to bypass. My votes go to Avira and Nod32, ZoneAlarm could also go into this category but it tends to be buggy sometimes. Comodo and Avast are the ones i would avoid at all costs.